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Memory CD8+ T cells balance pro- and anti-inflammatory activity by reprogramming cellular acetate handling at sites of infection

doi: 10.1016/j.nbd.2008.11.011 26 ChenZ.ZhangH

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Therefore, the strategic targeting of MDSCs to convert GBM from a "cold" tumor, refractory to immune response, to a "hot" tumor that responds favorably to immunotherapy holds significant therapeutic promise (Fig